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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1055715Generated: November 1, 2026

3-(4-Methylpiperazin-1-yl)-5-(pentafluoro-lambda6-sulphanyl)benzoic acid trifluoroacetate → 3-(4-Methylpiperazin-1-yl)-N-{4-methyl-3-[6-(pyridin-3-yl)-1H-imidazo[1,2-b]pyrazol-1-yl]-phenyl}-5-(pentafluoro-lambda6-sulphanyl)benzamide

https://huagongshe.com/reaction/1055715

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(4-Methylpiperazin-1-yl)-5-(pentafluoro-lambda6-sulphanyl)benzoic acid trifluoroacetateHCID 89699560—
Reactant4-Methyl-3-[6-(pyridin-3-yl)-1H-imidazo[1,2-b]pyrazol-1-yl]anilineHCID 89700023—
Product3-(4-Methylpiperazin-1-yl)-N-{4-methyl-3-[6-(pyridin-3-yl)-1H-imidazo[1,2-b]pyrazol-1-yl]-phenyl}-5-(pentafluoro-lambda6-sulphanyl)benzamideHCID 89700081—

Reaction Steps

50 mg (0.17 mmol) of the compound of Example 6A and 79.6 mg (0.17 mmol) of the compound of Example 17A were reacted and worked up analogously to the procedure of Example 16. This gave 82 mg (77% of theory) of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09394309B2
Source datasetuspto-grants-2016_07
ORD IDord-9ed52056d2a141b3b83b5e215ae5a210
Source noteuspto-grants-2016_07