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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1055734Generated: November 1, 2026

4-Methyl-3-[6-(pyridin-3-yl)-1H-imidazo[1,2-b]pyrazol-1-yl]aniline → 3-tert-Butyl-5-(4-methylpiperazin-1-yl)-N-{4-methyl-3-[6-(pyridin-3-yl)-1H-imidazo[1,2-b]-pyrazol-1-yl]phenyl}benzamide

https://huagongshe.com/reaction/1055734

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Methyl-3-[6-(pyridin-3-yl)-1H-imidazo[1,2-b]pyrazol-1-yl]anilineHCID 89700023—
Reactant3-tert-Butyl-5-(4-methylpiperazin-1-yl)benzoic acid trifluoroacetateHCID 89700131—
Product3-tert-Butyl-5-(4-methylpiperazin-1-yl)-N-{4-methyl-3-[6-(pyridin-3-yl)-1H-imidazo[1,2-b]-pyrazol-1-yl]phenyl}benzamideHCID 89700230—

Reaction Steps

35 mg (0.12 mmol) of the compound of Example 6A and 47 mg (0.12 mmol) of the compound of Example 21A were reacted and worked up analogously to the procedure of Example 16. This gave 25 mg (95% pure, 38% of theory) of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09394309B2
Source datasetuspto-grants-2016_07
ORD IDord-7dea7f02b06a427da1d5717bf3c29620
Source noteuspto-grants-2016_07