HCID 89699730, compound → HCID 89700164, compound

HRID 1055735Notes

Reaction equation

HRID 1055735 reaction equation
[CH3:1][C:2]1[CH:8]=[CH:7][C:5]([NH2:6])=[CH:4][C:3]=1[N:9]1[C:16]2[N:12]([N:13]=[C:14]([C:17]3[CH:18]=[N:19][CH:20]=[CH:21][CH:22]=3)[CH:15]=2)[CH:11]=[CH:10]1.[C:23]([C:27]1[CH:28]=[C:29]([CH:33]=[C:34]([C:36]([OH:39])([CH3:38])[CH3:37])[CH:35]=1)[C:30](O)=[O:31])([CH3:26])([CH3:25])[CH3:24]>>[C:23]([C:27]1[CH:28]=[C:29]([CH:33]=[C:34]([C:36]([OH:39])([CH3:38])[CH3:37])[CH:35]=1)[C:30]([NH:6][C:5]1[CH:7]=[CH:8][C:2]([CH3:1])=[C:3]([N:9]2[C:16]3[N:12]([N:13]=[C:14]([C:17]4[CH:18]=[N:19][CH:20]=[CH:21][CH:22]=4)[CH:15]=3)[CH:11]=[CH:10]2)[CH:4]=1)=[O:31])([CH3:26])([CH3:24])[CH3:25]

Participants

3

Reactant 2

HCID 89699730HCID 89699730, compoundHCID 897000234-Methyl-3-[6-(pyridin-3-yl)-1H-imidazo[1,2-b]pyrazol-1-yl]aniline

Product 1

HCID 89700164HCID 89700164, compound

Procedure

40 mg (0.14 mmol) of the compound of Example 6A and 33 mg (0.14 mmol) of the compound of Example 28A were reacted and worked up analogously to the procedure of Example 33. This gave 31 mg (44% of theory) of the title compound.

Sources & evidence

ORD record
ord-12b185b637244ebcb4d3a9918fd6b467
Source dataset
uspto-grants-2016_07
Patent number
US09394309B2

Reaction notes

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