3-(Pentafluorosulfanyl)benzoic acid → HCID 89699964, compound

HRID 1055741Notes

Reaction equation

HRID 1055741 reaction equation
[O:1]([C:3]1[CH:9]=[CH:8][C:6]([NH2:7])=[CH:5][C:4]=1[N:10]1[C:17]2[N:13]([N:14]=[C:15]([C:18]3[CH:19]=[N:20][CH:21]=[CH:22][CH:23]=3)[CH:16]=2)[CH:12]=[CH:11]1)[CH3:2].[F:24][S:25]([F:38])([F:37])([F:36])([F:35])[C:26]1[CH:27]=[C:28]([CH:32]=[CH:33][CH:34]=1)[C:29](O)=[O:30]>>[CH3:2][O:1][C:3]1[CH:9]=[CH:8][C:6]([NH:7][C:29](=[O:30])[C:28]2[CH:32]=[CH:33][CH:34]=[C:26]([S:25]([F:38])([F:24])([F:35])([F:36])[F:37])[CH:27]=2)=[CH:5][C:4]=1[N:10]1[C:17]2[N:13]([N:14]=[C:15]([C:18]3[CH:19]=[N:20][CH:21]=[CH:22][CH:23]=3)[CH:16]=2)[CH:12]=[CH:11]1

Participants

3

Reactant 2

HCID 27792093-(Pentafluorosulfanyl)benzoic acidHCID 89699779HCID 89699779, compound

Product 1

HCID 89699964HCID 89699964, compound

Procedure

45 mg (0.15 mmol) of the compound of Example 10A and 37 mg (0.15 mmol) of 3-(pentafluoro-λ6-sulphanyl)benzoic acid were reacted and worked up analogously to the procedure of Example 16. This gave 72 mg (91% of theory) of the title compound.

Sources & evidence

ORD record
ord-74f287546cc44e0db3e85476b13392a1
Source dataset
uspto-grants-2016_07
Patent number
US09394309B2

Reaction notes

Loading…