HCID 89699787, compound → HCID 89699989, compound

HRID 1055748Notes

Reaction equation

HRID 1055748 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([C:7]2[CH:8]=[C:9]3[N:14]([C:15]4[CH:16]=[C:17]([CH:19]=[CH:20][CH:21]=4)[NH2:18])[CH:13]=[CH:12][N:10]3[N:11]=2)[CH:2]=1.[C:22]([C:24]1[CH:25]=[C:26]([CH:30]=[C:31]([S:33]([F:38])([F:37])([F:36])([F:35])[F:34])[CH:32]=1)[C:27](O)=[O:28])#[N:23]>>[C:22]([C:24]1[CH:25]=[C:26]([CH:30]=[C:31]([S:33]([F:37])([F:38])([F:34])([F:35])[F:36])[CH:32]=1)[C:27]([NH:18][C:17]1[CH:19]=[CH:20][CH:21]=[C:15]([N:14]2[C:9]3[N:10]([N:11]=[C:7]([C:3]4[CH:2]=[N:1][CH:6]=[CH:5][CH:4]=4)[CH:8]=3)[CH:12]=[CH:13]2)[CH:16]=1)=[O:28])#[N:23]

Participants

3

Reactant 2

HCID 89699787HCID 89699787, compoundHCID 896998123-Cyano-5-(pentafluoro-lambda6-sulphanyl)benzoic acid

Product 1

HCID 89699989HCID 89699989, compound

Procedure

Analogously to the process described in Example 26, 100 mg (0.363 mmol) of the compound of Example 62A and 117 mg (0.363 mmol) of the compound of Example 23A gave 62 mg (32% of theory) of the title compound. In this case, the reaction time was about 15 h.

Sources & evidence

ORD record
ord-295b90109de64885b27b50e47cc184ba
Source dataset
uspto-grants-2016_07
Patent number
US09394309B2

Reaction notes

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