Potassium Cation → 1-(2-{4-[3-(3,4-Dimethoxy-phenyl)-4,4-dimethyl-5-oxo-4,5-dihydro-pyrazol-1-yl]-piperidin-1-yl}-2-oxo-ethyl)-1,3-dihydro-2H-indol-2-one

HRID 105575Notes

Reaction equation

HRID 105575 reaction equation
[CH3:45][C:46]#[N:47].[Cl:1][CH2:2][C:3](=[O:4])[N:5]1[CH2:6][CH2:7][CH:8]([N:11]2[N:12]=[C:13]([c:19]3[cH:20][c:21]([O:27][CH3:28])[c:22]([O:25][CH3:26])[cH:23][cH:24]3)[C:14]([CH3:17])([CH3:18])[C:15]2=[O:16])[CH2:9][CH2:10]1.[K+:39].[K+:40].[O-:41][C:42]([O-:43])=[O:44].[O:29]=[C:30]1[CH2:31][c:32]2[cH:33][cH:34][cH:35][cH:36][c:37]2[NH:38]1>>[CH2:2]([C:3](=[O:4])[N:5]1[CH2:6][CH2:7][CH:8]([N:11]2[N:12]=[C:13]([c:19]3[cH:20][c:21]([O:27][CH3:28])[c:22]([O:25][CH3:26])[cH:23][cH:24]3)[C:14]([CH3:17])([CH3:18])[C:15]2=[O:16])[CH2:9][CH2:10]1)[N:38]1[C:30](=[O:29])[CH2:31][c:32]2[cH:33][cH:34][cH:35][cH:36][c:37]21

Participants

6

Reactant 5

HCID 813Potassium Cation2×HCID 6342AcetonitrileHCID 19660Carbonate IonHCID 321710OxindoleHCID 666166092-[1-(chloroacetyl)piperidin-4-yl]-5-(3,4-dimethoxyphenyl)-4,4-dimethyl-2,4-dihydro-3H-pyrazol-3-one

Product 1

HCID 251162991-(2-{4-[3-(3,4-Dimethoxy-phenyl)-4,4-dimethyl-5-oxo-4,5-dihydro-pyrazol-1-yl]-piperidin-1-yl}-2-oxo-ethyl)-1,3-dihydro-2H-indol-2-one

Sources & evidence

ORD record
ord-9945e632fb4d454fa80068c035e6a2e3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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