HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-((tert-Butoxycarbonyl)amino)cyclopropanecarboxylic acid → 1'H-spiro[cyclopropane-1,6'-pyrrolo[3,4-b]pyrrol]-4'(5'H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-((tert-Butoxycarbonyl)amino)cyclopropanecarboxylic acid | HCID 688396 | — |
| Reactant | 5,6-dihydropyrrolo[3,4-b]pyrrol-4(1H)-one | HCID 69403530 | — |
| Product | 1'H-spiro[cyclopropane-1,6'-pyrrolo[3,4-b]pyrrol]-4'(5'H)-one | HCID 89784179 | — |
Reaction Steps
This compound was prepared in a manner similar to that described for Intermediate 703, starting from 1-((tert-butoxycarbonyl)amino)cyclopropanecarboxylic acid. 1H NMR (400 MHz, DMSO-d6) δ ppm 11.08 (1H, br.), 7.53 (1H, s), 6.82 (1H, s), 6.11 (1H, d, J=2.2 Hz), 1.3 (2H, m), 1.27 (2H, m). m/z (ESI, +ve) 149.0 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09394297B2 |
| Source dataset | uspto-grants-2016_07 |
| ORD ID | ord-6d1e86debddf41aca8f9154f7522e9de |
| Source note | uspto-grants-2016_07 |