5,6-dihydropyrrolo[3,4-b]pyrrol-4(1H)-one → 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5,6-dihydropyrrolo[3,4-b]pyrrol-4(1H)-one

HRID 1055823Notes

Reaction equation

HRID 1055823 reaction equation
C[C@@H:2]1[C:6]2[NH:7][C:8]([B:10]3[O:14][C:13]([CH3:16])([CH3:15])[C:12]([CH3:18])([CH3:17])[O:11]3)=[CH:9][C:5]=2[C:4](=[O:19])[NH:3]1.N1C=CC2C(=O)NCC1=2>>[CH3:15][C:13]1([CH3:16])[C:12]([CH3:17])([CH3:18])[O:11][B:10]([C:8]2[NH:7][C:6]3[CH2:2][NH:3][C:4](=[O:19])[C:5]=3[CH:9]=2)[O:14]1

Participants

3

Reactant 2

HCID 694035305,6-dihydropyrrolo[3,4-b]pyrrol-4(1H)-oneHCID 89781988(R)-6-methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5,6-dihydropyrrolo[3,4-b]pyrrol-4(1H)-one

Product 1

HCID 897819912-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5,6-dihydropyrrolo[3,4-b]pyrrol-4(1H)-one

Procedure

This compound as a brown solid was prepared according to the procedure described for intermediate 705, using 5,6-dihydropyrrolo[3,4-b]pyrrol-4(1H)-one (703) as the starting material. m/z (ESI, +ve) 248.7 (M+H)+).

Sources & evidence

ORD record
ord-2443e5b5446f435d8103bb88dd512eb2
Source dataset
uspto-grants-2016_07
Patent number
US09394297B2

Reaction notes

Loading…