HuagongsheHuagongshe Chemistry Print Report · For research reference only
Stannane, tributyl(1-ethoxyethenyl)- → HCID 89782044, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Stannane, tributyl(1-ethoxyethenyl)- | HCID 619414 | — |
| Reactant | HCID 89782156 | HCID 89782156 | — |
| Catalyst | Bis(di-tert-butyl(4-dimethylaminophenyl)phosphine)dichloropalladium(II) | HCID 11714597 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 89782044 | HCID 89782044 | — |
Reaction Steps
A solution of 8-chloro-2-phenoxyquinoxaline (253 mg, 0.986 mmol), tributyl(1-ethoxyvinyl)stannane (499 μl, 1.478 mmol, Aldrich), and PdCl2(Amphos)2 (34.9 mg, 0.049 mmol) in toluene (9.9 ml) was stirred at 110° C. in a sealed tube for 16 h. Purification by silica gel (100% hexanes to 10% EtOAc/hexanes) provided 1-(3-phenoxyquinoxalin-5-yl)ethanone as a white solid. MS (ESI, pos. ion) m/z: 365.2 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09394297B2 |
| Source dataset | uspto-grants-2016_07 |
| ORD ID | ord-39d0fbf97ca74de5bb7120d39aa74967 |
| Source note | uspto-grants-2016_07 |