1-(2-Phenylethyl)pyrrolidin-3-amine → 4-methyl-N-[1-(2-phenylethyl)pyrrolidin-3-yl]-1-azabicyclo[2.2.2]octane-3-carboxamide

HRID 105621Notes

Reaction equation

HRID 105621 reaction equation
[CH3:1][C:2]12[CH:3]([C:10](=[O:11])[Cl:12])[CH2:4][N:5]([CH2:6][CH2:7]1)[CH2:8][CH2:9]2.[NH2:13][CH:14]1[CH2:15][N:16]([CH2:19][CH2:20][c:21]2[cH:22][cH:23][cH:24][cH:25][cH:26]2)[CH2:17][CH2:18]1>>[CH3:1][C:2]12[CH:3]([C:10](=[O:11])[NH:13][CH:14]3[CH2:15][N:16]([CH2:19][CH2:20][c:21]4[cH:22][cH:23][cH:24][cH:25][cH:26]4)[CH2:17][CH2:18]3)[CH2:4][N:5]([CH2:6][CH2:7]1)[CH2:8][CH2:9]2

Participants

3

Reactant 2

HCID 184118191-(2-Phenylethyl)pyrrolidin-3-amineHCID 184118744-Methylquinuclidine-3-carbonyl chloride

Product 1

HCID 184118674-methyl-N-[1-(2-phenylethyl)pyrrolidin-3-yl]-1-azabicyclo[2.2.2]octane-3-carboxamide

Sources & evidence

ORD record
ord-11b56d8794ff40ad81ad43779db9def2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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