HCID 89783476, compound → HCID 89784154, compound

HRID 1056236Notes

Reaction equation

HRID 1056236 reaction equation
[ClH:1].[NH2:2][CH2:3][C:4]1[NH:5][C:6]([C:12]2[CH:21]=[CH:20][CH:19]=[C:18]3[C:13]=2[N:14]=[C:15]([NH:23][C:24]([CH3:27])([CH3:26])[CH3:25])[C:16]([CH3:22])=[N:17]3)=[CH:7][C:8]=1[C:9]([OH:11])=[O:10].C(OC(NCC1NC(C2C=CC=C3C=2N=C(NC2(C)CC2)C(C)=N3)=CC=1C(OCC)=O)=O)(C)(C)C>>[ClH:1].[NH2:2][CH2:3][C:4]1[NH:5][C:6]([C:12]2[CH:21]=[CH:20][CH:19]=[C:18]3[C:13]=2[N:14]=[C:15]([NH:23][C:24]2([CH3:27])[CH2:26][CH2:25]2)[C:16]([CH3:22])=[N:17]3)=[CH:7][C:8]=1[C:9]([OH:11])=[O:10]

Participants

3

Reactant 2

HCID 89783476HCID 89783476, compoundHCID 89784387HCID 89784387, compound

Product 1

HCID 89784154HCID 89784154, compound

Procedure

This compound was prepared according to the procedures described for Intermediate (334c), using ethyl 24(tert-butoxycarbonyl)amino)methyl)-5-(2-methyl-3-((1-methylcyclopropyl)amino)quinoxalin-5-yl)-1H-pyrrole-3-carboxylate (357b) (0.25 g, 0.53 mmol) as starting material. Crude material was used without further purification. Assumed theoretical conversion. m/z (ESI, +ve) 352.0 (M+H)+.

Workup

  1. customThis compound was prepared
  2. customCrude material was used without further purification

Sources & evidence

ORD record
ord-a2e202e7b529487b8faf4e4a83b799db
Source dataset
uspto-grants-2016_07
Patent number
US09394297B2

Reaction notes

Loading…