Triphosgene → HCID 89783339, compound

Participants

Reaction Conditions

Reaction Steps

A glass microwave reaction vessel was charged with 2-amino-3-bromo-N-(2-(methylsulfonyl)ethyl)benzamide (480 mg, 1.494 mmol) and triphosgene (0.078 mL, 0.523 mmol, Fluka) in 1,4-dioxane (6 mL). The reaction mixture was stirred and heated in an Initiator microwave reactor (Personal Chemistry, Biotage AB, Inc., Upssala, Sweden) at 100° C. for 45 min. The mixture was cooled to RT and the solvent was removed to give the crude product 600 mg. MS (ESI, pos. ion) m/z: 347 (M+1).

Provenance & Evidence