HCID 58352566, compound → HCID 86652906, compound

HRID 1056460Notes

Reaction equation

HRID 1056460 reaction equation
[F:1][CH:2]([F:27])[CH2:3][O:4][C:5]1[N:9]([CH3:10])[N:8]=[C:7]([C:11]([F:14])([F:13])[F:12])[C:6]=1[CH:15](F)[S:16]([C:19]1[CH2:23][C:22]([CH3:25])([CH3:24])[O:21][N:20]=1)(=[O:18])=[O:17].[F:28]C1C(C)(C)ON=C1S(CC1C(C(F)(F)F)=NN(C)N=1)(=O)=O.CC1(C)ON=C(S(C(F)C2C(C(F)(F)F)=NN(C)N=2)(=O)=O)C1.CC1(C)ON=C(S(CC2C(C(F)(F)F)=NN(C)N=2)(=O)=O)C1.FC(F)COC1N(C)N=C(C(F)(F)F)C=1C(F)(F)S(C1CC(C)(C)ON=1)(=O)=O.CC1(C)ON=C(S(C(F)(F)C2C(C(F)(F)F)=NN(C)N=2)(=O)=O)C1.FC(F)COC1N(C)N=C(C(F)(F)F)C=1C(F)(F)S(C1C(F)C(C)(C)ON=1)(=O)=O.FC(F)(S(C1C(F)C(C)(C)ON=1)(=O)=O)C1C(C(F)(F)F)=NN(C)N=1>>[F:1][CH:2]([F:27])[CH2:3][O:4][C:5]1[N:9]([CH3:10])[N:8]=[C:7]([C:11]([F:14])([F:13])[F:12])[C:6]=1[CH2:15][S:16]([C:19]1[CH:23]([F:28])[C:22]([CH3:25])([CH3:24])[O:21][N:20]=1)(=[O:18])=[O:17]

Participants

9

Reactant 8

HCID 58352566HCID 58352566, compoundHCID 58352567HCID 58352567, compoundHCID 58352568HCID 58352568, compoundHCID 58352571HCID 58352571, compoundHCID 58352572HCID 58352572, compoundHCID 86652907HCID 86652907, compoundHCID 86652908HCID 86652908, compoundHCID 86652909HCID 86652909, compound

Product 1

HCID 86652906HCID 86652906, compound

Procedure

3-{[5-(2,2-difluoroethoxy)-1-methyl-3-trifluoromethyl-1H-pyrazol-4-yl]fluoromethanesulfonyl}-5,5-dimethyl-4,5-dihydroisoxazole (2-2); 4-(4-fluoro-5,5-dimethyl-4,5-dihydroisoxazole-3-sulfonylmethyl)-2-methyl-5-trifluoromethyl-2H-[1,2,3]triazole (2-3); 4-[(5,5-dimethyl-4,5-dihydroisoxazole-3-sulfonyl)fluoromethyl]-2-methyl-5-trifluoromethyl-2H-[1,2,3]triazole (2-4); 4-(5,5-dimethyl-4,5-dihydroisoxazole-3-sulfonylmethyl)-2-methyl-5-trifluoromethyl-2H-[1,2,3]triazole (2-5); 3-{[5-(2,2-difluoroethoxy)-1-methyl-3-trifluoromethyl-1H-pyrazol-4-yl]difluoromethanesulfonyl}-5,5-dimethyl-4,5-dihydroisoxazole (2-6); 4-[(5,5-dimethyl-4,5-dihydroisoxazole-3-sulfonyl)difluoromethyl]-2-methyl-5-trifluoromethyl-2H-[1,2,3]triazole (2-7); 3-{[5-(2,2-difluoroethoxy)-1-methyl-3-trifluoromethyl-1H-pyrazol-4-yl]difluoromethanesulfonyl}-4-fluoro-5,5-dimethyl-4,5-dihydroisoxazole (2-8); 4-[difluoro-(4-fluoro-5,5-dimethyl-4,5-dihydroisoxazole-3-sulfonyl)methyl]-2-methyl-5-trifluoromethyl-2H-[1,2,3]triazole (2-9);

Sources & evidence

ORD record
ord-549e5f1d21a74fe88e33c804994a468d
Source dataset
uspto-grants-2016_07
Patent number
US09398768B2

Reaction notes

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