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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1056579Generated: October 31, 2026

Hydrochloric Acid → HCID 73388151, compound

https://huagongshe.com/reaction/1056579

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 86711093HCID 86711093—
SolventEthyl AcetateHCID 8857—
ProductHCID 73388151HCID 73388151—

Reaction Steps

The title compound was prepared according to the procedure as described in Example 17 Step 3 using (5-(4-chlorophenyl)-3-(2,6-difluoro-3-(propylsulfonamido)benzoyl)-1H-pyrrolo[2,3-b]pyridin-1-yl)methyl 2-((tert-butoxycarbonyl)amino)acetate (46 mg, 0.07 mmol) and a saturated solution of HCl in EtOAc (2 mL). The title compound was obtained as a white solid (36 mg, 83.7%). The title compound was characterized by LC-MS and 1H NMR as shown below:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09399639B2
Source datasetuspto-grants-2016_07
ORD IDord-9e4ab18ef91743e49c1cf1de34c54735
Source noteuspto-grants-2016_07