HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 73388151, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 86711093 | HCID 86711093 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 73388151 | HCID 73388151 | — |
Reaction Steps
The title compound was prepared according to the procedure as described in Example 17 Step 3 using (5-(4-chlorophenyl)-3-(2,6-difluoro-3-(propylsulfonamido)benzoyl)-1H-pyrrolo[2,3-b]pyridin-1-yl)methyl 2-((tert-butoxycarbonyl)amino)acetate (46 mg, 0.07 mmol) and a saturated solution of HCl in EtOAc (2 mL). The title compound was obtained as a white solid (36 mg, 83.7%). The title compound was characterized by LC-MS and 1H NMR as shown below:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09399639B2 |
| Source dataset | uspto-grants-2016_07 |
| ORD ID | ord-9e4ab18ef91743e49c1cf1de34c54735 |
| Source note | uspto-grants-2016_07 |