Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1056580Generated: November 1, 2026

Hydrochloric Acid → HCID 73388153, compound

https://huagongshe.com/reaction/1056580

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 86711094HCID 86711094—
SolventEthyl AcetateHCID 8857—
ProductHCID 73388153HCID 73388153111.6%

Reaction Steps

A mixture of (5-(4-chlorophenyl)-3-(2,6-difluoro-3-(propylsulfonamido)benzoyl)-1H-pyrrolo[2,3-b]pyridin-1-yl)methyl 2-((tert-butoxycarbonyl)(methyl)amino)acetate (0.33 g, 0.48 mmol) and a saturated solution of HCl in EtOAc (3 mL) was stirred at rt for 3 h. The mixture was filtered to afford the title compound as a white solid (168 mg, 56%). The title compound was characterized by LCMS and 1H NMR as shown below:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09399639B2
Source datasetuspto-grants-2016_07
ORD IDord-f2f26bec961743129a158c061b76bb7a
Source noteuspto-grants-2016_07