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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1056588Generated: November 4, 2026

Hydrochloric Acid → HCID 86711101, compound

https://huagongshe.com/reaction/1056588

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 86711100HCID 86711100—
SolventEthyl AcetateHCID 8857—
ProductHCID 86711101HCID 86711101114.9%

Reaction Steps

A mixture of 1-(5-(4-chlorophenyl)-3-(2,6-difluoro-3-(propylsulfonamido)benzoyl)-1H-pyrrolo[2,3-b]pyridin-1-yl)ethyl 2-((tert-butoxycarbonyl)amino)-3-methylbutanoate (0.29 g, 0.39 mmol) and a saturated solution of HCl in EtOAc (4 mL) was stirred at rt for 2 h. The mixture was filtered to give the title compound as a white solid (0.15 g, 57%). The title compound was characterized by LC-MS and 1H NMR as shown below:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09399639B2
Source datasetuspto-grants-2016_07
ORD IDord-c85dc1501e6f4836bbc9124b2f5f5f1a
Source noteuspto-grants-2016_07