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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1056679Generated: November 2, 2026

Azetidine → HCID 118566571, compound

https://huagongshe.com/reaction/1056679

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAzetidineHCID 10422—
ReactantDiisopropylethylamineHCID 81531—
Reactant2,6-Dichloro-quinoline-5-carboxylic acid (4,4-difluorocyclohexylmethyl)-amideHCID 118555965—
ProductHCID 118566571HCID 118566571—

Reaction Steps

The title compound was synthesized according to the procedure described in example 1 using 2,6-dichloro-quinoline-5-carboxylic acid (4,4-difluoro-cyclohexylmethyl)-amide, DIPEA and azetidine. 1H NMR (400 MHz, DMSO-d6) δ ppm 8.75 (1H), 7.88 (1H), 6.69 (1H), 4.49 (m, 4H), 3.24 (m, 2H), 2.40 (m, 2H), 2.04 (m, 2H), 1.85 (m, 2H), 1.74-1.76 (m, 3H), 1.27-1.30 (m, 2H). m/z: 394 [M+H].

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09399623B2
Source datasetuspto-grants-2016_07
ORD IDord-4ce2d46ab39b47579fca9fcb10e2cfb8
Source noteuspto-grants-2016_07