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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1056741Generated: October 30, 2026

Diisopropylethylamine → HCID 118566647, compound

https://huagongshe.com/reaction/1056741

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiisopropylethylamineHCID 81531—
Reactant(3R)-(+)-3-(Dimethylamino)pyrrolidineHCID 2758521—
Reactant2,6-Dichloro-quinoline-5-carboxylic acid (4,4-difluorocyclohexylmethyl)-amideHCID 118555965—
ProductHCID 118566647HCID 118566647—

Reaction Steps

The title compound was synthesized according to the procedure described in example 1 using 2,6-dichloro-quinoline-5-carboxylic acid (4,4-difluoro-cyclohexylmethyl)-amide, DIPEA and (R)-3-dimethylamino-pyrrolidine. 1H NMR (400 MHz, DMSO-d6) δ ppm 7.75 (1H), 7.48 (2H), 6.69 (1H), 3.66 (m, 2H), 3.49 (m, 2H), 3.32 (m, 2H), 2.36 (s, 6H), 2.06 (m, 2H), 1.85 (m, 2H), 1.74-1.76 (m, 5H), 1.27-1.30 (m, 2H). m/z: 451 [M+H]

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09399623B2
Source datasetuspto-grants-2016_07
ORD IDord-0b1c3216c2aa41ba94e5308f4e0f9e9b
Source noteuspto-grants-2016_07