Cesium carbonate → HCID 131736446, compound

Participants

Reaction Steps

The title compound was synthesized according to the procedure described in example 125 using 2,6-dichloro-quinoline-5-carboxylic acid (4,4-difluoro-cyclohexyl methyl)-amide, cyclohexene-1-yl-boronic acid, cesium carbonate and tetrakis(triphenylphosphine)palladium (0). 1H NMR (400 MHz, DMSO-d6): δ 8.83 (t, J=5.9 Hz, 1H), 7.89-8.00 (m, 3H), 7.73-7.76 (m, 1H), 6.91 (s, 1H), 3.27 (t, J=6.2 Hz, 2H), 2.65-2.66 (m, 2H), 2.31-2.32 (m, 2H), 1.86-2.01 (m, 2H), 1.74-1.76 (m, 3H), 1.65-1.67 (m, 6H), 1.27-1.30 (m, 2H). m/z: 419 [M+H]+

Provenance & Evidence