Triethylsilane → HCID 118566584, compound

Participants

Reaction Steps

The title compound was synthesized according to the procedure described in example 126 using 6-chloro-2-cyclopent-1-enyl-quinoline-5-carboxylic acid ((1R,3R)-1-hydroxy-3-methyl-cyclohexylmethyl)-amide, palladium on carbon and triethylsilane. 1H NMR (400 MHz, DMSO-d6): δ 8.59 (t, J=6.01 Hz, 1H), 8.10 (d, J=8.82 Hz, 1H), 7.96 (d, J=9.22 Hz, 1H), 7.75 (d, J=9.23 Hz, 1H), 7.59 (d, J=8.81 Hz, 1H), 3.35-3.39 (m, 1H), 3.29 (s, 2H), 2.06-2.09 (m, 2H), 1.78-1.87 (m, 4H), 1.69-1.75 (m, 3H), 1.47-1.61 (m, 4H), 1.47-1.48 (m, 1H), 1.23-1.29 (m, 1H), 1.03 (t, J=12.81 Hz, 1H), 0.83-0.84 (m, 3H), 0.73-0.76 (m, 1H). m/z: 401.2 [M+H]+

Provenance & Evidence