HRID1056956

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：Nc1ccc(Br)c(Oc2ccc(F)cc2F)c1[N+](=O)[O-]

HCID118093920

未命名化合物

结构：Cn1cc(B2OC(C)(C)C(C)(C)O2)c2ccn(COCC[Si](C)(C)C)c2c1=O

HCID123210853

未命名化合物

PRODUCTS

生成物

结构：Cn1cc(-c2ccc(N)c([N+](=O)[O-])c2Oc2ccc(F)cc2F)c2ccn(COCC[Si](C)(C)C)c2c1=O

HCID123242082

未命名化合物

PROCEDURE

实验过程

This compound was synthesized according to the procedure of Example 10, Step 5, using 4-bromo-3-(2,4-difluorophenoxy)-2-nitroaniline and 6-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-{[2-(trimethylsilyl)ethoxy]methyl}-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one as the starting materials. LCMS calculated for C26H29F2N4O5Si (M+H)+: m/z=543.2. found: 543.2.

WORKUP

后处理

customThis compound was synthesized

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-017cfd004877476d8c38f8803db4752c
来源数据集: uspto-grants-2016_07
DOI: 10.6084/m9.figshare.5104873.v1
专利: US09399640B2
来源说明: uspto-grants-2016_07

反应 SMILES

Br[C:2]1[CH:8]=[CH:7][C:5]([NH2:6])=[C:4]([N+:9]([O-:11])=[O:10])[C:3]=1[O:12][C:13]1[CH:18]=[CH:17][C:16]([F:19])=[CH:15][C:14]=1[F:20].[CH3:21][N:22]1[CH:27]=[C:26](B2OC(C)(C)C(C)(C)O2)[C:25]2[CH:37]=[CH:38][N:39]([CH2:40][O:41][CH2:42][CH2:43][Si:44]([CH3:47])([CH3:46])[CH3:45])[C:24]=2[C:23]1=[O:48]>>[NH2:6][C:5]1[CH:7]=[CH:8][C:2]([C:26]2[C:25]3[CH:37]=[CH:38][N:39]([CH2:40][O:41][CH2:42][CH2:43][Si:44]([CH3:45])([CH3:47])[CH3:46])[C:24]=3[C:23](=[O:48])[N:22]([CH3:21])[CH:27]=2)=[C:3]([O:12][C:13]2[CH:18]=[CH:17][C:16]([F:19])=[CH:15][C:14]=2[F:20])[C:4]=1[N+:9]([O-:11])=[O:10]