Cyclobutylcarbinol → 4-Bromo-3-(cyclobutylmethoxy)-N-methyl-2-nitroaniline

HRID 1056963Notes

Reaction equation

HRID 1056963 reaction equation
[Br:1][C:2]1[CH:9]=[CH:8][C:5]([NH:6][CH3:7])=[C:4]([N+:10]([O-:12])=[O:11])[C:3]=1F.[CH:14]1([CH2:18][OH:19])[CH2:17][CH2:16][CH2:15]1>>[Br:1][C:2]1[CH:9]=[CH:8][C:5]([NH:6][CH3:7])=[C:4]([N+:10]([O-:12])=[O:11])[C:3]=1[O:19][CH2:18][CH:14]1[CH2:17][CH2:16][CH2:15]1

Participants

3

Reactant 2

HCID 78130CyclobutylcarbinolHCID 1180938324-Bromo-3-fluoro-N-methyl-2-nitroaniline

Product 1

HCID 1180938704-Bromo-3-(cyclobutylmethoxy)-N-methyl-2-nitroaniline

Procedure

This compound was synthesized according to the procedure of Example 11, Step 1, using 4-bromo-3-fluoro-N-methyl-2-nitroaniline and cyclobutylmethanol as the starting materials. LCMS calculated for C12H16BrN2O3 (M+H)+: m/z=315.0, 317.0. found: 315.0, 317.0.

Workup

  1. customThis compound was synthesized

Sources & evidence

ORD record
ord-dae2fc49103a4fbfaf3109d5986073d2
Source dataset
uspto-grants-2016_07
Patent number
US09399640B2

Reaction notes

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