Bromoacetonitrile → HCID 118093837, compound

HRID 1056996Notes

Reaction equation

[Br:1][C:2]1[CH:7]=[N:6][C:5]([OH:8])=[C:4]2[N:9]([S:12]([C:15]3[CH:20]=[CH:19][C:18]([CH3:21])=[CH:17][CH:16]=3)(=[O:14])=[O:13])[CH:10]=[CH:11][C:3]=12.Br[CH2:23][C:24]#[N:25]>>[Br:1][C:2]1[C:3]2[CH:11]=[CH:10][N:9]([S:12]([C:15]3[CH:20]=[CH:19][C:18]([CH3:21])=[CH:17][CH:16]=3)(=[O:14])=[O:13])[C:4]=2[C:5](=[O:8])[N:6]([CH2:23][C:24]#[N:25])[CH:7]=1

Participants

Reactant 2

HCID 11534Bromoacetonitrile

HCID 178427323HCID 178427323, compound

Product 1

HCID 118093837HCID 118093837, compound

Procedure

This compound was synthesized according to the procedure of Example 83, Step 1, using 4-bromo-1-[(4-methylphenyl)sulfonyl]-1H-pyrrolo[2,3-c]pyri din-7-ol and bromoacetonitrile as the starting materials. LCMS calculated for C16H13BrN3O3S (M+H)+: m/z=406.0, 408.0. found: 405.9, 407.9.

Workup

customThis compound was synthesized

Sources & evidence

ORD record: ord-c535cdc6cd8343e98081127852fcabaa
Source dataset: uspto-grants-2016_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09399640B2

Reaction notes

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