6-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-tosyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-one → HCID 118093873, compound

HRID 1057009Notes

Reaction equation

HRID 1057009 reaction equation
Br[C:2]1[CH:3]=[CH:4][C:5]2[O:9][CH:8]=[N:7][C:6]=2[C:10]=1[O:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1.[CH3:18][N:19]1[CH:24]=[C:23](B2OC(C)(C)C(C)(C)O2)[C:22]2[CH:34]=[CH:35][N:36]([S:37]([C:40]3[CH:45]=[CH:44][C:43]([CH3:46])=[CH:42][CH:41]=3)(=[O:39])=[O:38])[C:21]=2[C:20]1=[O:47]>>[CH3:18][N:19]1[CH:24]=[C:23]([C:2]2[CH:3]=[CH:4][C:5]3[O:9][CH:8]=[N:7][C:6]=3[C:10]=2[O:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[C:22]2[CH:34]=[CH:35][N:36]([S:37]([C:40]3[CH:45]=[CH:44][C:43]([CH3:46])=[CH:42][CH:41]=3)(=[O:39])=[O:38])[C:21]=2[C:20]1=[O:47]

Participants

3

Reactant 2

HCID 867210626-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-tosyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-oneHCID 118093824HCID 118093824, compound

Product 1

HCID 118093873HCID 118093873, compound

Procedure

This compound was synthesized according to the procedure of Example 10, Step 5, using 5-bromo-4-phenoxy-1,3-benzoxazole and 6-methyl-1[(4-methylphenyl)sulfonyl]-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one as the starting materials. LCMS calculated for C28H22N3O5S (M+H)+: m/z=512.1. found: 512.0.

Workup

  1. customThis compound was synthesized

Sources & evidence

ORD record
ord-fcfdbcf22740498a9aafec987e356dda
Source dataset
uspto-grants-2016_07
Patent number
US09399640B2

Reaction notes

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