HCID 69157955, compound → HCID 87717364, compound

Participants

Reaction Steps

To a stirring solution of methyl 2-(8-{[(4-nitro phenyl)methoxy]carbonylamino}-2-[N-(3-(1,2,3,4-tetrahydropyridino[2,3-b]pyridin-7-yl)propyl) carbamoyl]-1H,3H,4H,5H-benzo[e]azepin-5-yl)acetate in ethanol (0.05 M) at room temperature was added 10% Pd/C (0.10M). After stirring 4 hr, under hydrogen, at balloon pressure, the reaction mixture was filtered through celite. The reaction solvent was removed by rotary evaporation. The residue was purified by flash chromatography (50% EtOAc/Hexane). EI-MS m/z 480 (M+H)+.

Provenance & Evidence