HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methoxyaniline → 7-Acetamino-1-(3-methoxyanilino)-4-(4-pyridylmethyl)phthalazine hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methoxyaniline | HCID 10824 | — |
| Reactant | 7-Acetamino-1-chloro-4-(4-pyridylmethyl)phthalazine | HCID 22741951 | — |
| Solvent | 1-Butanol | HCID 263 | — |
| Product | 7-Acetamino-1-(3-methoxyanilino)-4-(4-pyridylmethyl)phthalazine hydrochloride | HCID 22741989 | — |
Reaction Steps
By analogy with 25, 300 mg (0.96 mmol) 7-acetamino-1-chloro-4-(4-pyridylmethyl)phthalazine is reacted in 3.9 ml 1-butanol with 321 μl (2.88 mmol) 3-methoxyaniline to obtain title compound: m.p.: 156-159° C.; HPLC: tRet(Grad5-40)=11.0; FAB MS (M+H)+=400.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06514974B2 |
| Source dataset | uspto-grants-2003_02 |
| ORD ID | ord-552bae08db634870a6469d754c5d2629 |
| Source note | uspto-grants-2003_02 |