HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium hydroxide, monohydrate → 212142-75-1
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium hydroxide, monohydrate | HCID 168937 | — |
| Reactant | HCID 53651284 | HCID 53651284 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 212142-75-1 | HCID 22386455 | — |
Reaction Steps
100 mg (0.214 mMol) of rac benzoic acid-[4-(4-chloroanilino)phthalazin-1-yl](pyridin-4-yl)-methyl ester in 2 ml dioxane, 1 ml methanol and 1 ml water are saponified with 9.9 mg (0.235 mmol) lithiumhydroxide monohydrate. After 16 h, the title compound is filtered off: m.p. 196-197° C., FAB MS (M+H)+=363.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06514974B2 |
| Source dataset | uspto-grants-2003_02 |
| ORD ID | ord-f06dda8508674b21af33897bb5bbca46 |
| Source note | uspto-grants-2003_02 |