4-Amino-3,5-dichloropyridine → (+/-)-4-[(3,5-Dichloro-4-pyridyl)aminocarbonyl]-3-[(3,5-dichloro-4-pyridyl)aminocarbonyl]methyl-7-methoxy-2,3-dihydrobenzofuran

Participants

Role	Name	HCID	Charge
Reactant	4-Amino-3,5-dichloropyridine	HCID 89888	—
Reactant	(+/-)-3-Carboxymethyl-4-(3,5-dichloro-4-pyridylamino-carbonyl)-7-methoxy-2,3-dihydrobenzofuran	HCID 22734342	—
Product	(+/-)-4-[(3,5-Dichloro-4-pyridyl)aminocarbonyl]-3-[(3,5-dichloro-4-pyridyl)aminocarbonyl]methyl-7-methoxy-2,3-dihydrobenzofuran	HCID 22734471	17%

Reaction Steps

Substantially the same procedure as in Example 13 was repeated using Compound 9 (0.30 g) obtained in Example 9 and 4-amino-3,5-dichloropyridine to give Compound 32 (0.06 g, 17%) as a white solid.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US06514996B2
Source dataset	uspto-grants-2003_02
ORD ID	ord-24174e3800d7464587b4565311e7a773
Source note	uspto-grants-2003_02