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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1057915Generated: October 31, 2026

Pyrrolidine → HCID 40805129, compound

https://huagongshe.com/reaction/1057915

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyrrolidineHCID 31268—
Reactant7-Methoxy-1-benzofuran-2-carboxylic acidHCID 606037—
ProductHCID 40805129HCID 40805129—

Reaction Steps

Substantially the same procedure as in Example 219 was repeated using a starting material, 7-methoxybenzofuran-2-carboxylic acid, and pyrrolidine to give 2-Pyrrolidinylcarbonyl-7-methoxybenzofuran (Compound 309a). Successively, it was formylated to give 2-pyrrolidinyl-carbonyl-4-formyl-7-methoxybenzofuran (Compound 309b), then compound 309b was reacted with methylamine hydrochloride to give compound 309 as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06514996B2
Source datasetuspto-grants-2003_02
ORD IDord-be2cffe778784a5293c75c19a1183c32
Source noteuspto-grants-2003_02