HuagongsheHuagongshe Chemistry Print Report · For research reference only
P-Anisidine → 7-methoxy-N-(4-methoxyphenyl)benzofuran-2-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | P-Anisidine | HCID 7732 | — |
| Reactant | 7-Methoxy-1-benzofuran-2-carboxylic acid | HCID 606037 | — |
| Product | 7-methoxy-N-(4-methoxyphenyl)benzofuran-2-carboxamide | HCID 22733867 | — |
Reaction Steps
Substantially the same procedure as in Example 219 was repeated using a starting material, 7-methoxybenzofuran-2-carboxylic acid, and p-anisidine to give N-(4-methoxyphenyl)-7-methoxybenzofuran-2-carboxamide (Compound 399a). Successively, it was formylated to give N-(4-methoxyphenyl)-4-formyl-7-methoxybenzofuran-2-carboxamide (Compound 399b), then compound 399b was reacted with cyclobutylamine to give compound 399 as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06514996B2 |
| Source dataset | uspto-grants-2003_02 |
| ORD ID | ord-9e1b0347386f4b0789b32bbddbc23a8a |
| Source note | uspto-grants-2003_02 |