HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Fluoro-p-anisaldehyde → 1,1-Dimethylethyl 4-[4-(4-fluorophenyl)-2-oxo-3-(4-pyridinyl)-3-butenyl]-1-piperidinecarboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Fluoro-p-anisaldehyde | HCID 67696 | — |
| Reactant | 4-Fluorobenzaldehyde | HCID 68023 | — |
| Reactant | 4-Pyridinylacetone | HCID 80552 | — |
| Reactant | tert-Butyl 4-(2-oxo-3-(pyridin-4-yl)propyl)piperidine-1-carboxylate | HCID 22037457 | — |
| Product | 1,1-Dimethylethyl 4-[4-(4-fluorophenyl)-2-oxo-3-(4-pyridinyl)-3-butenyl]-1-piperidinecarboxylate | HCID 53804312 | — |
Reaction Steps
1,1-Dimethylethyl 4-[4-(4-fluorophenyl)-2-oxo-3-(4-pyridinyl)-3-butenyl]-1-piperidinecarboxylate was prepared by the same method as described for step 1 of Example A-1 by replacing 4-pyridylacetone and 3-fluoro-p-anisaldehyde with the ketone of step 2 of the present Example and 4-fluorobenzaldehyde, respectively.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06514977B1 |
| Source dataset | uspto-grants-2003_02 |
| ORD ID | ord-57551534f21c43d3b10ca5f003093cf8 |
| Source note | uspto-grants-2003_02 |