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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1058130Generated: October 31, 2026

Carbon Dioxide → 4-Chloro-2-methylbenzoic acid

https://huagongshe.com/reaction/1058130

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCarbon DioxideHCID 280—
Reactant2-Bromo-5-chlorotolueneHCID 84476—
ReactantCID 53628100HCID 178418400—
Product4-Chloro-2-methylbenzoic acidHCID 348269—

Reaction Steps

in stage a) 2-bromo-5-chlorotoluene is reacted with a secondary or tertiary organolithium compound, particularly preferably sec-butyllithium, and CO2 to give 4-chloro-2-methylbenzoic acid,

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06515143B2
Source datasetuspto-grants-2003_02
ORD IDord-15f6dad5715e4f5fa7c2f86d49eea5ec
Source noteuspto-grants-2003_02