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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1058131Generated: November 2, 2026

Methyl iodide → 4-chloro-2-methyl-5-(methylsulfonyl)Benzoic acid

https://huagongshe.com/reaction/1058131

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl iodideHCID 6328—
ReactantSodium SulfiteHCID 24437—
ReactantChlorosulfonic acidHCID 24638—
Reactant4-Chloro-2-methylbenzoic acidHCID 348269—
Product4-chloro-2-methyl-5-(methylsulfonyl)Benzoic acidHCID 10824478—

Reaction Steps

in stage b) 4-chloro-2-methylbenzoic acid is reacted with chlorosulfonic acid, sodium sulfite and methyl iodide to give 2-methyl-4-chloro-5-methylsulfonylbenzoic acid,

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06515143B2
Source datasetuspto-grants-2003_02
ORD IDord-4fa07af5f9624e01a259d317b3f507e4
Source noteuspto-grants-2003_02