Carbamimidoylazanium Chloride → N-(2-Methyl-4,5-bis(methylsulfonyl)benzoyl)guanidine

HRID 1058133Notes

Reaction equation

[CH3:1][C:2]1[CH:10]=[C:9]([S:11]([CH3:14])(=[O:13])=[O:12])[C:8]([S:15]([CH3:18])(=[O:17])=[O:16])=[CH:7][C:3]=1[C:4](Cl)=[O:5].[Cl-].[NH2:20][C:21]([NH2:23])=[NH2+:22]>>[NH2:22][C:21]([NH2:23])=[N:20][C:4](=[O:5])[C:3]1[CH:7]=[C:8]([S:15]([CH3:18])(=[O:17])=[O:16])[C:9]([S:11]([CH3:14])(=[O:13])=[O:12])=[CH:10][C:2]=1[CH3:1]

Participants

Reactant 2

HCID 5460839Carbamimidoylazanium Chloride

HCID 110882142-Methyl-4,5-di(methylsulfonyl)benzoyl chloride

Product 1

HCID 9799487N-(2-Methyl-4,5-bis(methylsulfonyl)benzoyl)guanidine

Procedure

in stage e) 2-methyl-4,5-di(methylsulfonyl)benzoyl chloride is reacted with guanidinium chloride to give N-diaminomethylene-2-methyl-4,5-di(methylsulfonyl)benzamide.

Sources & evidence

ORD record: ord-73de887bd61a47ea843933363b66f165
Source dataset: uspto-grants-2003_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06515143B2

Reaction notes

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