3,5,5-Trimethylhexanoic acid → n-(3,5,5-Trimethylhexanoyl)-2-octyldodecylamine

Participants

Reaction Steps

3.6 g of 3,5,5-trimethylhexanoic acid and 6.8 g of 2-octyldodecylamine were mixed together in the tube of a microwave machine (Maxidigest™ MX 350 from the company Prolabo; frequency 2450±50 MHz, modulable power 300 W). After irradiation for about 50 minutes at 170° C.±10° C., the reaction mixture was dissolved in heptane and then purified on silica. 7 g of the desired amide were obtained.

Provenance & Evidence