Hydrogen Bromide → HCID 86585142, compound

Participants

Reaction Steps

Hydrogen bromide gas was bubbled through a suspension of 2-chloro-4-(diazoacetyl)benzoic acid, methyl ester (400 mg, 1.7 mmol) in diethyl ether (30 mL) for 10 min. The solvent was evaporated and the residue was triturated with diethyl ether/hexane and filtered to give 4-(bromoacetyl)-2-chlorobenzoic acid, methyl ester (385 mg, 79% yield) as a colorless solid.

Provenance & Evidence