反应详情

An emulsion of camphene in surfactant solution was prepared as in Example 1 (substituting camphene for ibuprofen). The hot camphene emulsion was pumped (peristaltic pump) at 6 lhr−1 through a cooled coil, to reduce the emulsion temperature to 20° C., then fed directly into a continuous sonication vessel (approximately 30 ml sonicated volume) fitted with a high intensity sonic probe (500 w). Two samples were collected. The first was untreated and the second was cooled rapidly in ice/water. The flow rate was then reduced to 2 lhr−1 and two samples collected and treated as above.

1. customto 20° C.
2. customfed directly into a continuous sonication vessel
3. custom(approximately 30 ml sonicated volume)
4. customfitted with a high intensity sonic probe (500 w)
5. customTwo samples were collected
6. temperaturethe second was cooled rapidly in ice/water
7. customcollected
8. additiontreated as above