HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Hydroxybenzoic Acid → 4-(4-(Trifluoromethyl)phenoxy)benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Hydroxybenzoic Acid | HCID 135 | — |
| Reactant | P-Nitrobenzotrifluoride | HCID 9821 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 4-(4-(Trifluoromethyl)phenoxy)benzoic acid | HCID 3673481 | — |
Reaction Steps
Following the general procedure of J. Polym. Sci., Polym. Chem. Ed. (1980), 18(10), 3069-80, 4-hydroxybenzoic acid, 4-nitro-1-(trifluoromethyl)benzene, and sodium hydride in DMF were heated at 130° C. to afford the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06518267B1 |
| Source dataset | uspto-grants-2003_02 |
| ORD ID | ord-72aa9766b9964a31bb7583d49c5faba1 |
| Source note | uspto-grants-2003_02 |