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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1058661Generated: November 3, 2026

4-Fluoro-3-(trifluoromethyl)benzaldehyde → 4-[(4-Methylphenyl)thio]-3-(trifluoromethyl)benzaldehyde

https://huagongshe.com/reaction/1058661

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluoro-3-(trifluoromethyl)benzaldehydeHCID 522269—
ReactantBenzaldehyde, 5-bromo-2-[(4-methylphenyl)thio]-HCID 18668950—
Product4-[(4-Methylphenyl)thio]-3-(trifluoromethyl)benzaldehydeHCID 18668916100%

Reaction Steps

Using 4-fluoro-5-(trifluoromethyl)benzaldehyde (0.20 g, 1.0 mmol), 4-[(4-methylphenyl)thio]-3-(trifluoromethyl)benzaldehyde (0.30 g, 100%) was obtained in a manner similar to the synthesis of 5-bromo-2-[(4-methylphenyl)thio]benzaldehyde.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06518268B1
Source datasetuspto-grants-2003_02
ORD IDord-20520e0cebd84c84af7f8a2eff6f70dc
Source noteuspto-grants-2003_02