Hydroxyamine hydrochloride → HCID 73991919, compound

Participants

Reaction Steps

A mixture of the 4-ethylsulfanyl-butan-2-one (13.6 g, 0.1 mol), sodium acetate trihydrate (68 g, 0.5 mol) and hydroxylamine hydrochloride (34.7 g, 0.5 mol) in 500 mL of ethanol was heated to refluxed for 3 hours. The mixture was cooled and concentrated in vacuo. The residue was diluted with water and extracted with ethyl acetate (2×200 mL). The organic solution was then washed with Brine, dried, filtered and concentrated in vacuo to afford 14.7 g of the oxime.

Provenance & Evidence