HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Pyridinebutanoic acid → 4-Pyridin-3-yl-butyryl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Pyridinebutanoic acid | HCID 114 | — |
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Catalyst | Dimethylformamide | HCID 6228 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 4-Pyridin-3-yl-butyryl chloride | HCID 10856162 | — |
Reaction Steps
To a solution of 247 mg (1.49 mmol) of 4-pyridin-3-yl-butyric acid in 10 mL CH2Cl2 was added one drop DMF and 2.3 mL (4.56 mmol) oxalyl chloride and the mixture stirred at rt for 4 h. The volatiles were evaporated under reduced pressure and the material used crude in the following procedure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06518285B2 |
| Source dataset | uspto-grants-2003_02 |
| ORD ID | ord-e20952f854d647e196629877f76e86df |
| Source note | uspto-grants-2003_02 |