Water → HCID 18669408, compound

Participants

Reaction Steps

A solution of 4.4 mL (52.93 mmol) 3-pyrrolidinol in 250 mL CH2Cl2 at 0° C. was added 8.4 mL (60.26 mmol) NEt3 and 8.2 mL (51.97 mmol) benzyloxyacetyl chloride. The reaction was stirred for 3.5 h and then poured into 400 mL H2O. The reaction was extracted with CH2Cl2, dried over MgSO4, filtered and rotary evaporated to yield 12.0 g (98%) of N-(benzyloxyacetyl)-3-pyrrolidinol as a yellow oil.

Provenance & Evidence