HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrazine, (4-chlorophenyl)-, hydrochloride (1:1) → 3-[5-chloro-2-(4-chlorophenyl)-1H-indol-3-yl]propanoic Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrazine, (4-chlorophenyl)-, hydrochloride (1:1) | HCID 71600 | — |
| Reactant | 5-(4-Chlorophenyl)-5-oxopentanoic acid | HCID 2733716 | — |
| Product | 3-[5-chloro-2-(4-chlorophenyl)-1H-indol-3-yl]propanoic Acid | HCID 9797746 | — |
Reaction Steps
Prepared from 4-chloro-δ-oxobenzenepentanoic acid and (4-chlorophenyl)hydrazine hydrochloride according to the method of Description 7. 1H NMR (250 MHz, DMSO-d6) δ2.55-2.61 (2H, m), 3.07-3.13 (2H, m), 7.16 (2H, d, J 12.6 Hz), 7.41 (2H, d, J 12.6 Hz), 7.62-7.71 (3H, m), 11.52 (1H, br s), and 12.19 (1H, br s). m/z (ES+) 331, 333 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06518273B1 |
| Source dataset | uspto-grants-2003_02 |
| ORD ID | ord-8cfadb137cd241d5916a5cbb8f346d6c |
| Source note | uspto-grants-2003_02 |