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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1058956Generated: October 26, 2026

Isopropyl iodide → 1-(3-Isopropoxyphenyl)piperazine

https://huagongshe.com/reaction/1058956

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIsopropyl iodideHCID 6362—
Reactanttert-Butyl 4-(3-hydroxyphenyl)piperazine-1-carboxylateHCID 18669061—
Product1-(3-Isopropoxyphenyl)piperazineHCID 18669058—

Reaction Steps

Prepared from 1,1-dimethylethyl 4-(3-hydroxyphenyl)-1-piperazinecarboxylate (Description 21) and 2-iodopropane according to the method of Description 22. 1H NMR (250 MHz, CDCl3) δ1.34 (6H, d, J 6 Hz), 3.63-3.78 (8H, m), 4.51-4.60 (1H, m), 6.78-6.84 (2H, m), and 7.30-7.37 (1H, m).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06518273B1
Source datasetuspto-grants-2003_02
ORD IDord-2e9ab042496d41519b8779ada9183572
Source noteuspto-grants-2003_02