Phenylboronic Acid → 4-(2-Methoxyphenyl)-1-{3-[5-methyl-2-(4-phenylphenyl)-1H-indol-3-yl]-1-oxopropyl}piperazine

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Prepared from 1-{3-[2-(4-bromophenyl)-5-methyl-1H-indol-3-yl]-1-oxopropyl}-4-(2-methoxyphenyl)piperazine (Example 1) and phenylboronic acid according to the method of Example 117. 1H NMR (360 MHz, CDCl3) δ8.05 (1H, br s), 7.71-7.61 (6H, m), 7.48-7.44 (3H, m), 7.39-7.35 (1H, m), 7.29-7.25 (1H, m), 7.06-6.98 (2H, m), 6.90-6.77 (3H, m), 3.82 (3H, s), 3.78 (2H, t, J 5.0 Hz), 3.46 (2H, t, J 5.0 Hz), 3.33 (2H, m), 2.92 (2H, t, J 5.0 Hz), 2.74 (4H, m), and 2.48 (3H, s). m/z (ES+) 530 (M+1).

Provenance & Evidence