Thionyl Chloride → HCID 18669513, compound

HRID 1058985Notes

Reaction equation

HRID 1058985 reaction equation
[CH2:1]([N:8]([CH2:21][C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1)[S:9]([C:12]1[CH:20]=[CH:19][C:15]([C:16](O)=[O:17])=[CH:14][CH:13]=1)(=[O:11])=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.S(Cl)([Cl:30])=O>>[CH2:1]([N:8]([CH2:21][C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1)[S:9]([C:12]1[CH:20]=[CH:19][C:15]([C:16]([Cl:30])=[O:17])=[CH:14][CH:13]=1)(=[O:11])=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 45523624-(dibenzylsulfamoyl)benzoic acid

Product 1

HCID 18669513HCID 18669513, compound

Procedure

A solution of 4-(dibenzylsulfamoyl)benzoic acid (24 g; 63 mmoles) in thionyl chloride (50 ml) was boiled under reflux for 2.5 hours and the excess of thionyl chloride removed under reduced pressure. 4-(dibenzylsulfamoyl)benzoyl chloride (25 g) was obtained as an oil which was used in the next step without purification.

Workup

  1. temperatureunder reflux for 2.5 hours
  2. customthe excess of thionyl chloride removed under reduced pressure

Sources & evidence

ORD record
ord-5193c9262c9f45de9fe412c194089dac
Source dataset
uspto-grants-2003_02
Patent number
US06518303B2

Reaction notes

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