HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dichloromethane → HCID 9839612, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 9907496 | HCID 9907496 | — |
| Product | HCID 9839612 | HCID 9839612 | 75% |
Reaction Steps
A solution of (±)-(1S,2S,3R,4R)-3-Acetamidomethyl-2-(N-t-butoxycarbonylamino)methyl-4-methoxycarbonylcyclopentane-1-carboxylic acid (62 mg, 0.16 mmol) in of dichloromethane (4 mL) was reacted with trifluoroacetic acid (1.0 mL) for 1 hour, at room temperature. The solution was concentrated in vacuo, at 25° C. The residue was treated with 1 N HCl and concentrated in vacuo to provide the title compound as a white solid (yield: 39 mg, 75%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06518305B1 |
| Source dataset | uspto-grants-2003_02 |
| ORD ID | ord-d270fb4601da479ba6bf2cf89316ef32 |
| Source note | uspto-grants-2003_02 |