HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Acetate → HCID 5317588, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | (8)-Gingerol | HCID 168114 | — |
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 5317588 | HCID 5317588 | — |
Reaction Steps
To a solution of [8]-gingerol (0.1 g) in EtOH (15 mL) was added dropwise a solution of NaBH4 (0.02 g in 1 mL H2O). The mixture was stirred at room temperature for 3 hrs. After acidification, EtOAc was added and organic layer was washed with water twice. Evaporation of solvent left a white solid which was purified by gradient chromatography to afford the title compound as a colourless liquid in quantitative yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06518315B1 |
| Source dataset | uspto-grants-2003_02 |
| ORD ID | ord-763d659ed08b4fbb86f943100e1d3d23 |
| Source note | uspto-grants-2003_02 |