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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1059033Generated: October 26, 2026

Ethyl Acetate → HCID 5317588, compound

https://huagongshe.com/reaction/1059033

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl AcetateHCID 8857—
Reactant(8)-GingerolHCID 168114—
ReactantSodium borohydrideHCID 4311764—
SolventEthanolHCID 702—
ProductHCID 5317588HCID 5317588—

Reaction Steps

To a solution of [8]-gingerol (0.1 g) in EtOH (15 mL) was added dropwise a solution of NaBH4 (0.02 g in 1 mL H2O). The mixture was stirred at room temperature for 3 hrs. After acidification, EtOAc was added and organic layer was washed with water twice. Evaporation of solvent left a white solid which was purified by gradient chromatography to afford the title compound as a colourless liquid in quantitative yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06518315B1
Source datasetuspto-grants-2003_02
ORD IDord-763d659ed08b4fbb86f943100e1d3d23
Source noteuspto-grants-2003_02