p-Toluenesulfonic acid → HCID 131723764, compound

Participants

Reaction Steps

Into a 300 ml rocking autoclave were charged 58.2 g (0.331 m) of 2-(n-pentyl)-1,3-dithiolane, 1.06 g of sulfur, 0.12 g of p-toluenesulfonic acid, and 1.87 g of cobalt polysulfide catalyst (added as a 43% slurry in toluene). The autoclave was pressurized with hydrogen and maintained between 1600 and 2200 psi while being heated to 250°. After cooling and venting, the crude product contained 57% of the hydrogenolysis product, CH3(CH2)5S(CH2)2SH, as determined by GC/MS. When this procedure is applied to the product of Example 1, the hydrogenolysis product, (MeO)3Si(CH2)3S(CH2)2SH, is obtained.

Provenance & Evidence