Cuminaldehyde → HCID 178438860, compound

HRID 1059067Notes

Reaction equation

HRID 1059067 reaction equation
C(C1C=CC([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=2[CH2:17][C:18]2[N:23]=[C:22]([C:24]3[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=3)[N:21]=[C:20]([OH:30])[CH:19]=2)=CC=1)C(C)C.[CH:31]([C:34]1[CH:41]=[CH:40][C:37](C=O)=[CH:36][CH:35]=1)([CH3:33])[CH3:32]>>[CH:31]([C:34]1[CH:41]=[CH:40][C:37]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=2[CH2:17][C:18]2[N:23]=[C:22]([C:24]3[CH:25]=[CH:26][CH:27]=[CH:28][CH:29]=3)[N:21]=[C:20]([OH:30])[CH:19]=2)=[CH:36][CH:35]=1)([CH3:33])[CH3:32]

Participants

3

Reactant 2

HCID 326CuminaldehydeHCID 178440743HCID 178440743, compound

Product 1

HCID 178438860HCID 178438860, compound

Procedure

Compound 6 was prepared using synthesis described for the Compound 5 using 4-isopropylbenzaldehyde in procedure 5. Purification was accomplished using column chromatography to provide the title compound as a solid (mp 106-108° C.). 1H-NMR (CDCl3) δ 8.15 (m, 2H); 7.45 (m, 3H); 7.3-7.1 (m, 9H); 6.3 (s, 1H); 5.4 (s, 1H); 2.9 (m, 1H); 1.2 (d, 6H). 13C-NMR (CDCl3) δ 171.0; 165.9; 156.6; 147.5; 141.5; 138.2; 132.1; 132.0; 129.5; 129.3; 128.9; 128.5; 128.0; 126.8; 126.6; 112.4; 58.5, 33.6; 23.9.

Workup

  1. customCompound 6 was prepared
  2. customsynthesis
  3. customPurification

Sources & evidence

ORD record
ord-01bfc2caf9d5417eaff912258aa40157
Source dataset
uspto-grants-2003_02
Patent number
US06518424B1

Reaction notes

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